Boye L Jensen Selected Research

Plasminogen

12/2020	Plasminogen Deficiency and Amiloride Mitigate Angiotensin II-Induced Hypertension in Type 1 Diabetic Mice Suggesting Effects Through the Epithelial Sodium Channel.
12/2019	Urokinase-type plasminogen activator contributes to amiloride-sensitive sodium retention in nephrotic range glomerular proteinuria in mice.
1/2019	Is urinary excretion of plasminogen associated with development of pre-eclampsia? An observational, explorative case-control study.
1/2018	Urine albumin is a superior predictor of preeclampsia compared to urine plasminogen in type I diabetes patients.
1/2018	Hydronephrosis is associated with elevated plasmin in urine in pediatric patients and rats and changes in NCC and γ-ENaC abundance in rat kidney.
11/2017	Physiology and pathophysiology of the plasminogen system in the kidney.
1/2016	Significant natriuretic and antihypertensive action of the epithelial sodium channel blocker amiloride in diabetic patients with and without nephropathy.
8/2015	Aberrant glomerular filtration of urokinase-type plasminogen activator in nephrotic syndrome leads to amiloride-sensitive plasminogen activation in urine.
12/2014	Amiloride lowers blood pressure and attenuates urine plasminogen activation in patients with treatment-resistant hypertension.
11/2012	Urinary plasmin activates collecting duct ENaC current in preeclampsia.

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Boye L Jensen Research Topics

Disease

29	Hypertension (High Blood Pressure) 01/2022 - 01/2008
16	Proteinuria 01/2022 - 09/2011
13	Nephrotic Syndrome (Syndrome, Nephrotic) 03/2020 - 02/2009
10	Albuminuria 01/2022 - 02/2012
10	Pre-Eclampsia (Preeclampsia) 01/2019 - 01/2012
9	Fibrosis (Cirrhosis) 01/2022 - 02/2013
7	Ureteral Obstruction 01/2022 - 08/2005
6	Diabetic Nephropathies (Diabetic Nephropathy) 01/2021 - 01/2012
6	Polyuria 11/2020 - 05/2007
5	Inflammation (Inflammations) 01/2022 - 01/2016
5	Type 2 Diabetes Mellitus (MODY) 01/2022 - 08/2014
5	Hypoxia (Hypoxemia) 01/2021 - 05/2004
4	Hydronephrosis 01/2022 - 07/2013
4	Body Weight (Weight, Body) 01/2022 - 09/2008
4	Ascites 01/2020 - 05/2005
4	Weight Loss (Weight Reduction) 12/2019 - 09/2007
3	Nephrogenic Diabetes Insipidus 11/2020 - 01/2014
3	Edema (Dropsy) 03/2020 - 08/2015
3	Nephrosis 12/2019 - 03/2015
3	Renal Cell Carcinoma (Grawitz Tumor) 01/2016 - 07/2006
3	Neoplasms (Cancer) 01/2016 - 05/2004
2	Ischemia 01/2022 - 05/2004
2	Hypertrophy 01/2022 - 11/2015
2	Chronic Renal Insufficiency 10/2021 - 01/2021
2	Acute Kidney Injury (Acute Renal Failure) 01/2021 - 01/2018
2	Polydipsia 11/2020 - 05/2009
2	Hyperkalemia 01/2018 - 12/2014
2	Endotoxemia 10/2013 - 08/2011
2	Weight Gain 09/2008 - 09/2007
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2007 - 05/2005
2	Pathologic Constriction (Stenosis) 05/2004 - 05/2004
1	Insulin Resistance 01/2022
1	Solitary Kidney 01/2022

Drug/Important Bio-Agent (IBA)

19	Fibrinolysin FDA Link 12/2020 - 02/2009
19	SodiumIBA 03/2020 - 05/2005
12	AldosteroneIBA 01/2022 - 05/2009
12	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2006
12	PlasminogenIBA 12/2020 - 02/2009
11	SaltsIBA 01/2020 - 01/2008
9	Amiloride (Midamor)FDA LinkGeneric 12/2020 - 12/2014
8	ReninIBA 12/2020 - 05/2009
8	Epithelial Sodium ChannelsIBA 12/2020 - 02/2009
7	Angiotensin IIIBA 12/2020 - 05/2004
6	Spironolactone (Aldactone)FDA LinkGeneric 01/2022 - 08/2006
6	prostasinIBA 12/2019 - 01/2015
6	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 12/2019 - 02/2009
6	Peptide Hydrolases (Proteases)FDA Link 12/2019 - 09/2011
5	AlbuminsIBA 01/2022 - 08/2014
5	LithiumIBA 03/2016 - 09/2008
4	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 01/2022 - 01/2007
4	AngiotensinsIBA 01/2022 - 05/2009
4	Messenger RNA (mRNA)IBA 01/2022 - 05/2004
4	CreatinineIBA 01/2021 - 12/2014
4	Serine Proteases (Serine Protease)IBA 01/2018 - 01/2012
3	Mineralocorticoid Receptor AntagonistsIBA 01/2022 - 02/2013
3	Atrial Natriuretic Factor (ANF)IBA 01/2021 - 03/2015
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2021 - 01/2008
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 03/2010
3	DiureticsIBA 01/2021 - 08/2014
3	Vasopressins (Vasopressin)IBA 11/2020 - 01/2014
3	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2020 - 04/2010
3	FurinIBA 12/2019 - 01/2015
3	Puromycin AminonucleosideIBA 12/2019 - 01/2012
3	PotassiumIBA 01/2019 - 02/2013
3	Arginine (L-Arginine)FDA Link 01/2019 - 10/2013
3	estropipate (Ogen)FDA LinkGeneric 01/2017 - 11/2012
3	Superoxides (Superoxide)IBA 10/2016 - 10/2013
3	Aquaporin 2IBA 04/2016 - 04/2010
3	EnzymesIBA 12/2015 - 01/2007
3	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2014 - 08/2011
3	Aquaporins (Water Channels)IBA 06/2012 - 08/2005
3	Oxygen (Dioxygen)IBA 01/2009 - 05/2004
3	AdrenomedullinIBA 01/2009 - 05/2004
2	sacubitril and valsartan sodium hydrate drug combinationIBA 01/2022 - 01/2021
2	Neprilysin (Neutral Endopeptidase)IBA 01/2022 - 01/2021
2	CytokinesIBA 01/2022 - 01/2021
2	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2022
2	Antihypertensive Agents (Antihypertensives)IBA 01/2022 - 01/2018
2	Vasopressin Receptors (Arginine Vasopressin Receptor)IBA 01/2020 - 04/2016
2	GlucocorticoidsIBA 01/2020 - 01/2007
2	NitratesIBA 01/2019 - 10/2016
2	Dietary SodiumIBA 01/2019 - 01/2008
2	Kallikreins (Kallikrein)IBA 03/2015 - 01/2015
2	parecoxibIBA 01/2014 - 09/2007
2	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2014 - 09/2007
2	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 10/2013 - 08/2011
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 10/2013 - 02/2013
1	dulaglutideIBA 01/2022
1	Complement System Proteins (Complement)IBA 01/2022
1	Dinoprostone (PGE2)FDA Link 01/2022
1	Sodium Chloride FDA LinkGeneric 01/2022
1	InterferonsIBA 01/2022
1	Insulin (Novolin)FDA Link 01/2022
1	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 01/2022
1	Technetium Tc 99m PentetateIBA 01/2022
1	Thromboxane Receptors (Thromboxane Receptor)IBA 01/2022

Therapy/Procedure

3	Nephrectomy 01/2022 - 01/2017
2	Renal Dialysis (Hemodialysis) 10/2021 - 08/2011
2	Therapeutics 01/2021 - 09/2008
1	Subcutaneous Injections 01/2022